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Megumi Shimoyama Selected Research

2',6'- dimethyltyrosyl- arginyl- phenylalanyl- lysinamide

11/2012Superior analgesic effect of H-Dmt-D-Arg-Phe-Lys-NH2 ([Dmt1]DALDA), a multifunctional opioid peptide, compared to morphine in a rat model of neuropathic pain.
1/2009Differential analgesic effects of a mu-opioid peptide, [Dmt(1)]DALDA, and morphine.
3/2005Differential respiratory effects of [Dmt1]DALDA and morphine in mice.

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Megumi Shimoyama Research Topics

Disease

6Pain (Aches)
02/2017 - 11/2004
5Hyperalgesia
02/2017 - 01/2005
5Neoplasms (Cancer)
02/2015 - 01/2002
3Neuralgia (Stump Neuralgia)
01/2018 - 11/2012
3Cancer Pain
11/2016 - 11/2008
2Peripheral Nervous System Diseases (PNS Diseases)
01/2018 - 02/2017
2Colonic Neoplasms (Colon Cancer)
01/2018 - 09/2003
2Colorectal Neoplasms (Colorectal Cancer)
02/2017 - 02/2014
2Chronic Pain
11/2016 - 07/2013
2Respiratory Insufficiency (Respiratory Failure)
11/2015 - 03/2005
2Breakthrough Pain
02/2015 - 02/2015
1Mitochondrial Diseases (Mitochondrial Disease)
01/2018
1Sleepiness
01/2018
1Intractable Pain
02/2017
1Opioid-Related Disorders (Opiate Addiction)
11/2016
1Substance Withdrawal Syndrome (Withdrawal Symptoms)
11/2016
1Bicuspid Aortic Valve Disease
11/2016
1Drug-Related Side Effects and Adverse Reactions
02/2015
1Hypersensitivity (Allergy)
02/2014
1Cold Hypersensitivity
02/2014
1Ganglion Cysts (Ganglion)
02/2014
1Constipation
07/2013
1Acute Pain
01/2009
1Hypoxia (Hypoxemia)
03/2005
1Inflammation (Inflammations)
01/2005
1Dyspnea (Shortness of Breath)
01/2002

Drug/Important Bio-Agent (IBA)

7Opioid Analgesics (Opioids)IBA
01/2018 - 11/2008
6Analgesics (Analgesic Drugs)IBA
02/2017 - 01/2009
5Morphine (MS Contin)FDA LinkGeneric
02/2015 - 02/2005
3Oxaliplatin (Eloxatin)FDA LinkGeneric
01/2018 - 02/2014
3Fentanyl (Sublimaze)FDA LinkGeneric
11/2015 - 02/2015
32',6'- dimethyltyrosyl- arginyl- phenylalanyl- lysinamideIBA
11/2012 - 03/2005
2Pharmaceutical PreparationsIBA
01/2018 - 02/2017
2OrexinsIBA
02/2017 - 01/2005
2TabletsIBA
02/2015 - 02/2015
2Opioid Peptides (Opioid Peptide)IBA
11/2012 - 03/2005
1Peptides (Polypeptides)IBA
01/2018
1PlatinumIBA
02/2017
1Duloxetine Hydrochloride (Cymbalta)FDA Link
02/2017
1SB 408124IBA
02/2017
1Dosage Forms (Dosage Form)IBA
11/2015
1NitrogenIBA
02/2014
1Oxygen (Dioxygen)IBA
02/2014
1tyrosyl-arginyl-phenylalanyl-lysinamide (DALDA)IBA
11/2012
1Naloxone (Narcan)FDA LinkGeneric
03/2005
1N-Methylaspartate (NMDA)IBA
02/2005
1Antisense OligonucleotidesIBA
02/2005
1Messenger RNA (mRNA)IBA
02/2005
1LigandsIBA
02/2005
1NMDA receptor A1IBA
02/2005
1Formaldehyde (Formol)FDA Link
02/2005
1Endothelin-1 (Endothelin 1)IBA
11/2004
1Furosemide (Lasix)FDA LinkGeneric
01/2002

Therapy/Procedure

3Analgesia
02/2015 - 01/2005
2Drug Therapy (Chemotherapy)
01/2018 - 02/2017
2Ligation
11/2012 - 09/2002
2Palliative Care (Palliative Therapy)
06/2012 - 09/2003
1Intraperitoneal Injections
02/2017
1Epidural Analgesia
11/2016
1Therapeutics
11/2016
1Pain Management
09/2003